Gavi vaccines prevent 2.2 million deaths in 2025
In 2025, Gavi-supported vaccines prevented more than 2.2 million deaths, marking the highest annual figure in the organization's history. This achievement is part of a broader trend of increasing vaccine coverage and effectiveness in lower-income countries.
In 2025, vaccines supported by Gavi prevented more than 2.2 million future deaths, which averages out to roughly 6,000 lives saved every day. This marks the highest number of lives saved in a single year since Gavi began its operations. These figures are part of the 2021 to 2025 strategic period, a timeframe that saw over 7.8 million deaths averted and more than 351 million children immunized. These results come at a difficult time for many nations where health systems are under pressure from conflict, climate shocks, and a reduction in official development assistance. Since 2000, Gavi-supported vaccines have saved more than 23 million lives in total.
Across the 57 Gavi-supported countries, the under-five mortality rate fell from 59 to 52.6 deaths per 1,000 live births between 2019 and 2024. This exceeded the 10% reduction target, with vaccines against pneumococcal disease, rotavirus, and Haemophilus influenzae type b (Hib) serving as primary drivers of the decline. In 2025, Gavi reached more than 73 million children, the highest annual immunization figure ever recorded. This brings the total number of children immunized with Gavi support since 2000 to over 1.3 billion. The organization also managed several vaccine introductions and outbreak responses, which helped increase coverage for diseases such as measles and polio.
Coverage for the third dose of the diphtheria, tetanus, and pertussis vaccine (DTP3) reached 82% in Gavi-supported nations, bringing the gap between these countries and the 85% global average to its narrowest point ever. In 2025, more than 35 million girls were fully immunized against HPV, an effort that aids in the long-term prevention of cervical cancer. Since Gavi's inception, over 95 million girls have been protected from the virus. Moving forward, the organization is expanding its work to address emerging threats like malaria. In 2025, malaria vaccines were introduced in 24 African countries, representing one of the fastest rollouts in history. With steady support and better access, Gavi aims to continue reducing mortality and improving health outcomes for children in lower-income countries.
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